Raw Material Gw0742 CAS 317318-84-6 Raw Powder with High Quality 99%

• Customization: Available
• CAS No.: 317318-84-6
• Formula: C21h17f4no3s2
• Model NO.: 317318-84-6
• EINECS: 1532714-185-1
• Type: Synthesis Material Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• Product Name: Gw0742
• Assay: 99%
• CAS: 317318-84-6
• Mf: C21h17f4no3s2
• Molecular Weight: 471.49
• Application: Intermediate for Muscle Building
• Transport Package: Dry and Cool
• Specification: 1kg/Aluminum Foil Bag, 25kg/Cardboard Drum
• Trademark: Gina
• Origin: Shaanxi, China
• Production Capacity: 50000 Kilogram/ Month

Product Description

GW0742
UsesA small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes
UsesA small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
Biological ActivityPotent and highly selective PPAR δ agonist. EC 50 values are 0.001, 1.1 and 2 μ M for transactivation of human PPAR δ , - α , and - γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.

Product Name:	GW0742
CAS:	317318-84-6
MF:	C21H17F4NO3S2
Product Categories:	GLP;PP;APIs;GLP-1
storage temp.	Store at -20°C
solubility	DMSO:3mg/mL (0.73 mM)

Effects
1. Lowers cholesterol levels
2. Minimizes gut inflammation
3. Improves lipid profile
Side Effects
1. Increased heart size (cardiomegaly)
2. Enlargement of heart in mice in just 24 hours
3. No human-based clinical trials